Thermo Fisher Scientific ATP1A3 Polyclonal Antibody
Rabbit polyclonal antibody specific to human ATP1A3. Validated for IHC (paraffin) applications. Provides high specificity through antigen affinity purification. Supplied in PBS with glycerol for stability. For research use only.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC-P): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ATP1A3. Recombinant protein control fragment (Product # RP-102977) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790921 |
Product Specific Information
Immunogen sequence: DKKDDKDSPK KNKGKERRDL DDLKKE
Target Information
The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for the ATP-dependent transport of sodium and potassium across the cell membrane. This membrane-bound enzyme is related to other ATPases including sarcoplasmic and endoplasmic reticulum calcium ATPase (SERCA) and plasma membrane calcium ATPase (PMCA).
The sodium/potassium ATPase consists of a large, multipass, transmembrane catalytic subunit (alpha subunit) and an associated smaller glycoprotein (beta subunit). There are three isoforms of the alpha subunit (alpha 1, alpha 2, alpha 3) and two isoforms of the beta subunit (beta 1, beta 2), encoded by two multigene families. These isoforms exhibit tissue-specific and developmental expression patterns. The alpha-3 subunit is found in neuronal, skeletal, and cardiac muscle, lung, and stomach tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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