Thermo Fisher Scientific PTPN7 Monoclonal Antibody (OTI3H8), TrueMAB
PTPN7 단백질을 인식하는 Mouse Monoclonal Antibody로, Western Blot과 IHC(P) 실험에 적합합니다. 고순도 Affinity chromatography 정제, PBS/BSA/glycerol buffer로 안정화되어 있으며, 연구용으로만 사용 가능합니다.
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- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H8 |
| Immunogen | Full length human recombinant protein of human PTPN7 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.85 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase family. PTPs are signaling molecules that regulate cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This gene is preferentially expressed in hematopoietic cells and acts as an early response gene in lymphokine-stimulated cells.
The noncatalytic N-terminus of this PTP interacts with MAP kinases and suppresses MAP kinase activities.
It is involved in T cell antigen receptor signaling through dephosphorylation of molecules related to the MAP kinase pathway.
Two alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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