
Thermo Fisher Scientific SEPT5 Polyclonal Antibody, Biotin
SEPT5 단백질을 인식하는 Biotin 결합 토끼 다클론 항체로, WB, IHC, ELISA, IP에 사용 가능. Human, Mouse, Rat 반응성. 합성 펩타이드(aa 300-350) 면역원 사용. 고순도 친화 크로마토그래피 정제. -20°C 보관.
- 카탈로그번호
- SEPT5-BIOTIN
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 300–350 on SEPT5 protein |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene belongs to the septin family of nucleotide-binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are conserved across species and are involved in cytoskeletal organization. Disruption of septin function can interfere with cytokinesis, leading to multinucleate or polyploid cells.
The SEPT5 gene is located on chromosome 22q11, a region frequently deleted in DiGeorge and velocardiofacial syndromes. Translocation events involving SEPT5 and the MLL gene have been reported in acute myeloid leukemia. Two main transcripts (2.2 kb and 3.5 kb) are known, differing by polyadenylation signal usage. An alternatively spliced variant with a distinct 5′ end has also been identified.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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