Thermo Fisher Scientific LSM11 Polyclonal Antibody
Human LSM11 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS 버퍼에 40% 글리세롤을 포함합니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용됩니다.
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Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human LSM11. Recombinant protein control fragment (Product #RP-96909). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643579 |
Product Specific Information
Immunogen sequence:
RSVPSSLQAS AREESRSELS GRTTRTDGSS VGGTFSRATT LSRGQSRKKK RKPKVDYQQV FTRHINQIFI RGENVLLV
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 99%
Target Information
LSm11 is a 360 amino acid protein that localizes to the nucleus and belongs to the LSm subfamily of snRNP Sm proteins.
It contains an N-terminal domain necessary for pre-mRNA cleavage and binds specifically to U7 snRNA, playing a role in cell cycle regulation and cell growth.
The gene encoding LSm11 maps to human chromosome 5, which comprises nearly 6% of the human genome.
Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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