
Thermo Fisher Scientific EGR2 Monoclonal Antibody (OTI1B12)
EGR2 단백질을 표적하는 Mouse 모노클로날 항체로, Western blot, IHC(P), ICC/IF에 사용 가능. 인간 시료 반응성. 액상 형태로 1 mg/mL 농도, PBS/BSA/Glycerol 완충액에 보관. -20°C에서 보관하며 동결/해동 반복은 피해야 함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 156–476 of EGR2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723114 |
Target Information
The EGR2 gene encodes the early growth response 2 protein, a transcription factor that binds DNA to regulate gene expression. This protein is essential for the formation and maintenance of myelin, which insulates nerve cells and ensures efficient nerve impulse transmission. Defects or mutations in EGR2 can lead to demyelinating neuropathies such as Charcot-Marie-Tooth disease type 1D or 4E, or Dejerine-Sottas syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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