Thermo Fisher Scientific CD147 Recombinant Mouse Monoclonal Antibody (11F3)
CD147 단백질을 인식하는 마우스 리콤비넌트 단클론 항체로, Western blot, IHC, ICC, Flow cytometry, ELISA 등 다양한 응용에 사용 가능. HEK293 세포에서 발현되며, 고순도의 액상 형태로 제공. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:50–1:200 |
| ELISA | Assay-dependent |
Product Specifications
| Specification | Detail |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | 11F3 |
| Immunogen | Recombinant Human CD147 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.65 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.03% Proclin 300 |
| Storage Conditions | -20°C or -80°C if preferred |
| Shipping Conditions | Wet ice |
| RRID | AB_3092489 |
Target Information
CD147 (also known as basigin, neurothelin, OX-47, 5A11, CE9, M6, EMMPRIN, extracellular matrix metalloproteinase inducer, TCSF, tumour cell-derived collagenase-stimulatory factor) is a 50–60 kDa glycoprotein with multiple glycosylated forms.
It is a plasma membrane protein important in spermatogenesis, embryo implantation, neural network formation, and tumor progression, and belongs to the immunoglobulin superfamily.
CD147 is highly expressed in metabolically active cells such as lymphoblasts, inflammatory cells, brown adipocytes, and malignant tumor cells.
It facilitates cell surface expression of monocarboxylate transporter proteins and extracellular matrix metalloproteinases, regulates integrin functions, and plays roles in cell development, activation, fetal development, and retinal function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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