Thermo Fisher Scientific Persephin Polyclonal Antibody
Human, Mouse, Rat에 반응하는 Rabbit Polyclonal Persephin 항체. Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Protein A로 정제된 1 mg/mL 액상 형태로 제공되며, -20°C에서 보관. 신경영양 인자 Persephin 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human Persephin (amino acids 51–156) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Persephin is a disulfide-linked, homodimeric neurotrophic factor structurally related to GDNF, artemin, and neurturin. These proteins belong to the cysteine-knot family of growth factors that form stable dimeric structures. Persephin signals through a multicomponent receptor system composed of RET and one of four GFRα (α1–α4) receptors. GFRα4, first identified in chicken, is the preferential binding subunit for persephin. Persephin promotes the survival of ventral midbrain dopaminergic neurons and motor neurons after sciatic nerve axotomy, and, like GDNF, promotes ureteric bud branching. Unlike GDNF and neurturin, persephin does not support the survival of peripheral neurons.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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