Thermo Fisher Scientific CHRNA10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:400

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide (C)RRHEDWKRLARVMDR, corresponding to amino acid residues 411- 425 of rat nAChRalpha10 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CHRNA10,uniProtId:Q9JLB5-1,ncbiNodeId:10114,antigenRange:411-425,antigenLength:447,antigenImageFileName:PA5-77506_CHRNA10_Q9JLB5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-77506_CHRNA10_Q9JLB5-1_Rabbit_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.8 mg/mL

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2735647

Product Specific Information

Product is shipped at room temperature as a lyophilized powder and should be stored at -20 °C upon receipt. Reconstitution: add 50 µL of deionized water.

Target Information

Ionotropic receptor with a probable role in the modulation of auditory stimuli. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.