Thermo Fisher Scientific CHRNA10 Polyclonal Antibody
Rabbit polyclonal antibody against CHRNA10 for Western blot applications. Recognizes rat nAChR alpha10 residues 411–425. Supplied lyophilized, 0.8 mg/mL concentration. Shipped at room temperature, store at -20°C after reconstitution.
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Applications
- Western Blot (WB): Tested dilution 1:400
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide (C)RRHEDWKRLARVMDR, corresponding to amino acid residues 411–425 of rat nAChR alpha10 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.8 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2735647 |
Product Specific Information
Product is shipped at room temperature as a lyophilized powder and should be stored at -20°C upon receipt.
Reconstitution: add 50 µL of deionized water.
Target Information
Ionotropic receptor with a probable role in the modulation of auditory stimuli.
Agonist binding may induce an extensive conformational change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
The channel is permeable to divalent cations including calcium, whose influx may activate a potassium current that hyperpolarizes the cell membrane.
In the ear, this may reduce basilar membrane motion, alter auditory nerve fiber activity, and protect against acoustic trauma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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