Thermo Fisher Scientific Phospho-SHIP2 (Tyr1135) Polyclonal Antibody
Phospho-SHIP2 (Tyr1135) 폴리클로날 항체로 인간, 마우스, 랫트 시료에서 인산화된 INPPL1 검출 가능. Western blot 및 IHC(P) 실험에 적합. 고순도 정제 및 안정적 PBS/glycerol 저장. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human INPPL1 (Accession O15357), corresponding to amino acid residues around phosphorylated Tyr1135 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816126 |
Product Specific Information
Antibody detects endogenous levels of INPPL1 only when phosphorylated at Tyr1135.
Target Information
The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase involved in the regulation of insulin function. It also regulates epidermal growth factor receptor turnover and actin remodeling. Additionally, this gene supports metastatic growth in breast cancer and serves as a valuable biomarker for breast cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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