Thermo Fisher Scientific DTYMK Polyclonal Antibody
Rabbit polyclonal antibody targeting human Thymidylate kinase (DTYMK). Suitable for Western blot and immunoprecipitation. Supplied as liquid unconjugated form at 1 mg/mL concentration. Essential for DNA synthesis research and pyrimidine analog drug pat...
- 판매단위
- pk
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Thermo Fisher Scientific DTYMK Polyclonal Antibody
Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 20 µL/mg of lysate |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A region between residue 162 to 212 of human Thymidylate kinase |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis.
DTYMK is essential for DNA synthesis and serves as an intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), a chemotherapeutic drug used for several solid tumors.
The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8.
DTYMK mRNA levels and enzyme activities are regulated at the level of the cell cycle and cell growth pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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(원본 이미지 파일: A305-652A-M_DTYMK_P23919-1_Rabbit.svg, A305-652A-M_DTYMK_P23919-1_Rabbit_PDP.jpeg)
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