Thermo Fisher Scientific CHD3 Polyclonal Antibody
CHD3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, IP 등 다양한 응용에 적합. 항원 친화 크로마토그래피로 정제된 고순도 항체. Human 및 Mouse 반응성. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1950 and 2000 of human chromodomain helicase DNA binding protein 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
- Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
Target Information
This gene encodes a member of the CHD family of proteins characterized by chromo domains and SNF2-related helicase/ATPase domains. The protein is part of the Mi-2/NuRD histone deacetylase complex, which remodels chromatin by deacetylating histones. Chromatin remodeling is crucial for transcription and other cellular processes. Autoantibodies against CHD3 are found in some dermatomyositis patients. Three alternatively spliced transcripts encoding different isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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