Thermo Fisher Scientific TLR8 Monoclonal Antibody (4C6)
인간 TLR8 단백질을 인식하는 Mouse IgG2b 단일클론 항체. Western Blot 및 ELISA에 적합. 친화 크로마토그래피로 정제된 액상형 제품. PBS(pH 7.4) 버퍼에 보존제로 무첨가. -20°C에서 보관, 동결/해동 반복은 피해야 함.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4C6 |
| Immunogen | TLR8 (NP_619542, 723–825 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
RISHLPSGFL SEVSSLKHLD LSSNLLKTIN KSALETKTTT KLSMLELHGN PFECTCDIGD FRRWMDEHLN VKIPRLVDVI CASPGDQRGK SIVSLELTTC VSD
Target Information
The TLR8 protein is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved across species and recognize pathogen-associated molecular patterns (PAMPs) expressed on infectious agents, mediating cytokine production for effective immune responses.
TLR8 is predominantly expressed in lung and peripheral blood leukocytes and is located near TLR7 on chromosome X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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