Thermo Fisher Scientific MAGEB18 Polyclonal Antibody
인간 MAGEB18 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC(P) 분석에 적합. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol 완충액에 보관. 암 관련 항원 연구 및 종양 면역학 연구용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human MAGEB18. Recombinant protein control fragment (Product # RP-95711) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2643681 |
Product Specific Information
Immunogen sequence:
STTNAIAPVS CSSNEGASSQ DEKSLGSSRE AEGWKEDPLN KKVVSLVHFL LQKYETKEPI T
Sequence identity with orthologs:
- Mouse: 38%
- Rat: 41%
Target Information
The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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