Thermo Fisher Scientific ATP1A3 Polyclonal Antibody
Rabbit polyclonal antibody recognizing ATP1A3 protein. Validated for WB and ELISA in mouse and rat samples. Supplied as liquid, unconjugated, affinity purified. Suitable for research on sodium/potassium ATPase function and membrane localization.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing amino acids 1–60 of human ATP1A3 (NP_6895091) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.76 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | −20°C, avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806277 |
Product Specific Information
- Immunogen sequence: MGDKKDDKDS PKKNKGKERR DLDDLKKEVA MTEHKMSVEE VCRKYNTDCV QGLTHSKAQE
- Positive Samples: Mouse liver, Rat liver
- Cellular Location: Cell membrane, Multi-pass membrane protein
Target Information
The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms. It mediates the ATP-dependent transport of sodium and potassium across the cell membrane. This enzyme is related to other ATPases such as SERCA and PMCA. The sodium/potassium ATPase consists of a catalytic alpha subunit and a smaller glycoprotein beta subunit.
There are three alpha isoforms (α1, α2, α3) and two beta isoforms (β1, β2), each showing tissue-specific expression. The α3 subunit is primarily expressed in neuronal, skeletal, and cardiac muscle, as well as lung and stomach tissues.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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