Thermo Fisher Scientific GADD45A Polyclonal Antibody
GADD45A 단백질을 검출하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 인간 및 생쥐 시료에 반응하며, 고순도의 Affinity chromatography로 정제되었습니다. PBS와 50% glycerol 용액에 보관되며, -20°C에서 안정적으로 저장 가능합니다.
- 카탈로그번호
- PA5114736
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human GADD45A (Accession P24522), corresponding to amino acid residues M1–A43 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899372 |
Product Specific Information
This antibody detects endogenous levels of total GADD45A.
Target Information
GADD45 alpha, beta, and gamma are an evolutionarily conserved family of nuclear proteins functioning as stress sensors for cellular physiological and environmental damage. These proteins are essential for activation of the G2/M checkpoint induced by UV radiation or alkylating agents. The GADD45-induced G2/M checkpoint is regulated through inactivation of Cdc2–cyclin B1 kinase. GADD45 forms a complex with p21 and Cdc2, serving as a core for interaction with other cell cycle regulators.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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