Thermo Fisher Scientific HM13 Polyclonal Antibody
Thermo Fisher Scientific의 HM13 Polyclonal Antibody는 마우스 HM13 단백질을 인식하는 토끼 유래 IgG 항체로, Western blot에 최적화되어 있습니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of mouse HM13 (aa 240–289) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2691372 |
Product Specific Information
This target displays homology in the following species:
Cow: 93% | Dog: 93% | Guinea Pig: 93% | Horse: 93% | Human: 100% | Mouse: 93% | Rabbit: 93% | Rat: 93% | Zebrafish: 92%
Target Information
Catalyzes intramembrane proteolysis of some signal peptides after cleavage from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm.
Required for generating lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides.
May play a role in graft rejection and in the removal of signal peptides attached to hepatitis C virus core protein after initial proteolytic processing.
Involved in intramembrane cleavage of PSEN1 and XBP1 isoform 1 in a DERL1/RNF139-dependent manner.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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