Thermo Fisher Scientific T43 Polyclonal Antibody
다중 응용 분야(WB, IHC, ICC, ELISA)에 적합한 Rabbit Polyclonal Antibody. 인간, 마우스, 랫트 반응성. IFT43 단백질(아미노산 111–208)에서 유래한 KLH 접합 펩타이드로 면역화. 고순도 Protein A 정제, 1 mg/mL 농도, -20°C 보관.
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Thermo Fisher Scientific T43 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human IFT43, amino acids 111–208 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
IFT43, encoded by C14ORF179, is a subunit of the intraflagellar transport complex A (IFT-A) of primary cilia.
IFT-A is involved in retrograde ciliary transport along axonemal microtubules.
Defects in IFT-A subunits are associated with skeletal ciliopathies such as Sensenbrenner syndrome, Jeune syndrome, and Ellis-van-Creveld syndrome.
Mutations in C14ORF179 have been linked to Sensenbrenner syndrome. (PMID: 21378380)
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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