Thermo Fisher Scientific MYH7 Polyclonal Antibody
MYH7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인체, 마우스, 랫트 반응성. IHC 및 ELISA에 적합하며 고순도 Protein A 정제 제품. 심근 및 골격근 연구용으로 사용.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
ELISA
- Tested Dilution: 1:5,000–1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human MYH7 (amino acids 1350–1390) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Muscle myosin is a hexameric protein containing two heavy chain subunits, two alkali light chain subunits, and two regulatory light chain subunits.
This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin, expressed predominantly in normal human ventricle and skeletal muscle tissues rich in slow-twitch type I fibers.
Changes in expression levels of MYH7 and the alpha heavy chain correlate with cardiac contractile velocity.
Altered expression is observed during thyroid hormone depletion and hemodynamic overloading.
Mutations in MYH7 are associated with familial hypertrophic cardiomyopathy, myosin storage myopathy, dilated cardiomyopathy, and Laing early-onset distal myopathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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