Thermo Fisher Scientific PPARGC1B Polyclonal Antibody
Human PPARGC1B 단백질을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 0.2 mg/mL 농도의 액상 형태. 단기 4°C, 장기 -20°C 보관 권장. 연구용 전용 제품.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human PPARGC1B. Recombinant protein control fragment (Product #RP-106289) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663928 |
Product Specific Information
Immunogen sequence:
IKHSLGKEIAL SLPSPEGLSL KATPGAAHKL PKKHPERSEL LSHLRHATAQ PASQAGQKRP FSCSFGDHDY CQVLR
Highest antigen sequence identity to the following orthologs:
- Mouse: 80%
- Rat: 80%
Target Information
PGC-1 beta is a tissue-specific co-activator that enhances the activity of estrogen receptor alpha.
The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner.
Ectopic expression of this protein has been shown to lead to increased mitochondrial number and basal oxygen consumption.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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