Thermo Fisher Scientific KCNS1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 0.2–1.0 µg/mL

Product Specifications

Product Specific Information

This target displays homology in the following species:
Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 93%; Rabbit: 89%; Rat: 93%; Zebrafish: 82%

Target Information

Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials.

The alpha subunits are of two types:

1. Those that are functional by themselves
2. Those that are electrically silent but capable of modulating the activity of specific functional alpha subunits

The KCNS1 protein is not functional by itself but can form heteromultimers with member 1 and member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. KCNS1 belongs to the S subfamily of the potassium channel family.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.