Thermo Fisher Scientific PDGFRA Monoclonal Antibody (2D2-1A11)

Applications

Tested Dilution

Publications

Western Blot (WB)

1-5 µg/mL

-

ELISA (ELISA)

0.03 ng/mL

-

in situ PLA (PLA)

1:1200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG1, kappa

Class

Monoclonal

Type

Antibody

Clone

2D2-1A11

Immunogen

PDGFRA (AAH15186, 25 a.a. approximately 218 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PDGFRA (CD140a),uniProtId:P16234-1,ncbiNodeId:9606,antigenRange:1-1089,antigenLength:1089,antigenImageFileName:H00005156-M01_PDGFRA_CD140a_P16234-1_House_mouse.svg,antigenImageFileNamePDP:H00005156-M01_PDGFRA_CD140a_P16234-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: LSLPSILPNE NEKVVQLNSS FSLRCFGESE VSWQYPMSEE ESSDVEIRNE ENNSGLFVTV LEVSSASAAH TGLYTCYYNH TQTEENELEG RHIYIYVPDP DVAFVPLGMT DYLVIVEDDD SAIIPCRTTD PETPVTLHNS EGVVPASYDS RQGFNGTFTV GPYICEATVK GKKFQTIPFN VYALKGTCII SFLL

Target Information

PDGFRA is a cell surface receptor tyrosine kinase which binds members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.