Thermo Fisher Scientific CX3CR1 Polyclonal Antibody
CX3CR1 단백질을 인식하는 Rabbit Polyclonal Antibody로 Rat 시료에 반응. Western blot, IHC, Flow cytometry 등 다양한 응용 가능. Protein A로 정제된 액상형 항체로 안정적인 저장 및 높은 특이성 제공.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Flow Cytometry (Flow) | Assay-dependent |
| Immunoprecipitation (IP) | 1:300–1:800 |
| Neutralization (Neu) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant amino terminal fragment (Rat) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_558546 |
Product Specific Information
PA1-22487 detects CX3CR1 in Rat samples.
Target Information
CX3CR1 is one of the chemokine receptors required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven-transmembrane protein was identified as the receptor for the transmembrane molecule fractalkine and renamed CX3CR1. It serves as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractalkine. CX3CR1 mediates leukocyte migration and adhesion and is expressed in various human tissues and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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