Thermo Fisher Scientific HTRA3 Polyclonal Antibody
Human HTRA3 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot에 적합. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태(0.58 mg/mL)로 제공. U87-MG, SK-N-SH 세포에서 양성 대조로 사용 가능. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 104–378 of Human HTRA3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.58 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548379 |
Product Specific Information
- Recommended positive controls: U87-MG, SK-N-SH
- Predicted reactivity: Mouse (93%), Rat (92%), Pig (92%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
HtrA3 belongs to the human high-temperature requirement factor A (HtrA) family, also known as pregnancy-related serine protease. HtrA3 has two isoforms (long and short) produced by alternative splicing. Similar to HtrA1, HtrA3 binds to various TGF-beta proteins and inhibits signaling of BMP-4, BMP-2, and TGF-beta 1. It does not inhibit signaling from constitutively active BMP receptors, indicating inhibition occurs upstream of the cell surface receptor.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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