
Thermo Fisher Scientific Cdc40 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Cdc40 protein. Validated for ICC/IF applications with high specificity. Affinity-purified and supplied as a liquid in PBS with 40% glycerol. Suitable for research use in studying pre-mRNA splicing and cell cyc...
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human Cdc40. Recombinant protein control fragment (Product # RP-106131) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662169 |
Product Specific Information
Immunogen sequence:
VQYNPTYETMF APEFGPENPF RTQQMAAPRN MLSGYAEPAH INDFMFEQQR RTFATYGYAL DPSLDNHQVS AKYIGSVEEA EKNQGLTVFE TGQKKT
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 73%
Target Information
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is essential for the catalytic step II in the pre-mRNA splicing process. It is found in the spliceosome and contains seven WD repeats that function in protein-protein interactions. This protein shows sequence similarity to yeast Prp17 protein, which functions in both pre-mRNA splicing and cell cycle progression, suggesting a role in cell cycle regulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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