Thermo Fisher Scientific F10 Monoclonal Antibody (OTI1D12), TrueMAB
인간 F10 단백질을 인식하는 마우스 단클론 항체로, Western blot에 최적화되어 있습니다. 정제된 액상 형태로 제공되며, PBS/1% BSA/50% glycerol 용액에 보존됩니다. 연구용으로만 사용 가능하며, 동결-해동을 피해야 합니다.
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Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 41–488 of human F10 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Factor X undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by excision of the tripeptide RKR. The two chains are held together by one or more disulfide bonds. The light chain contains two EGF-like domains, while the heavy chain contains the catalytic domain homologous to other hemostatic serine proteases. The mature factor is activated by cleavage of the activation peptide by factor IXa (intrinsic pathway) or factor VIIa (extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca²⁺, and phospholipid during blood clotting. Mutations in this gene can cause factor X deficiency, a hemorrhagic condition of variable severity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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