Thermo Fisher Scientific Mouse IL-17D Recombinant Protein, PeproTech

Applications

Tested Dilution

Publications

ELISA (ELISA)

Assay-dependent

-

Functional Assay (Functional)

Assay-dependent

-

Product Specifications

Species

Mouse

Expression System

E. coli

Amino acid sequence

AGALRTGRRP ARPRDCADRP EELLEQLYGR LAAGVLSAFH HTLQLGPREQ ARNASCPAGG RAADRRFRPP TNLRSVSPWA YRISYDPARF PRYLPEAYCL CRGCLTGLYG EEDFRFRSTP VFSPAVVLRR TAACAGGRSV YAEHYITIPV GCTCVPEPDK SADSANSSMD KLLLGPADRP AGR

Molecular weight

40.6 kDa

Class

Recombinant

Type

Protein

Purity

≥ 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin concentration

<1 EU/µg

Activity

Determined by its ability to bind murine IL-17RB Fc Chimera in a functional ELISA.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Purification

purified

Contains

no preservative

Storage conditions

-20°C

Shipping conditions

Ambient

Product Specific Information

Recombinant Murine IL-17D is a 40.6 kDa, disulfide-linked homodimer of two 183 amino acid, polypeptide chains.

This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis

Target Information

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.