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Thermo Fisher Scientific SMURF2 Monoclonal Antibody (OTI5E4), TrueMAB
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Thermo Fisher Scientific

Thermo Fisher Scientific SMURF2 Monoclonal Antibody (OTI5E4), TrueMAB

상품 한눈에 보기

SMURF2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot에 최적화됨. 인간 유래 단백질(aa 151-440)을 면역원으로 사용. 고순도 Affinity chromatography 정제, 1 mg/mL 농도. PBS/BSA/glycerol buffer로 안정적 보관 가능.

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Thermo Fisher Scientific
카테고리
Monoclonal Antibodies
판매단위
pk

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마지막 업데이트 2025. 08. 04. 오후 06:14
Thermo Fisher Scientific TA806650 SMURF2 Monoclonal Antibody (OTI5E4), TrueMAB 100 ul pk판매 단위 pk ·
재고 확인 필요
600,200원VAT 포함 660,220원
재고문의·견적요청 옵션은 실시간 상담으로 납기를 확인해 드립니다 · 연구비 카드 결제 가능

Thermo Fisher Scientific · Thermo Fisher Scientific SMURF2 Monoclonal Antibody (OTI5E4), TrueMAB

Applications

  • Western Blot (WB): 1:2,000 dilution tested

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone OTI5E4
Immunogen Human recombinant protein fragment corresponding to amino acids 151–440 of human SMURF2 produced in E. coli
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

SMURF2 is an E3 ubiquitin-protein ligase that transfers ubiquitin from an E2 conjugating enzyme to target substrates. It interacts with SMAD1, SMAD2, and SMAD7 to promote their ubiquitination and proteasomal degradation. SMURF2 enhances the inhibitory activity of SMAD7 and reduces the transcriptional activity of SMAD2. Coexpression with SMAD1 significantly decreases SMAD1 protein levels and modestly reduces SMAD2 levels.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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