Thermo Fisher Scientific LCAT Polyclonal Antibody
LCAT 단백질을 인식하는 염소 폴리클로날 항체로, Western blot 및 IHC(P)에서 검증됨. 인간 시료에 반응하며 0.5 mg/mL 농도의 액상 형태로 제공. TBS(pH 7.3) 버퍼에 0.5% BSA 및 0.02% sodium azide 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-EDGDDTVATRSTE (aa 366–378) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2933934 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:2,000.
Target Information
Lecithin: cholesterol acyltransferase (LCAT) is the plasma enzyme responsible for most HDL cholesteryl esters in human plasma. In species with cholesteryl ester transfer protein (CETP), it also contributes to VLDL and LDL cholesteryl ester formation. LCAT plays a key role in reverse cholesterol transport by facilitating the movement of cholesterol from peripheral tissues back to the liver for excretion. LCAT deficiency leads to low plasma HDL levels, while overexpression increases HDL concentrations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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