Thermo Fisher Scientific VANGL2 Polyclonal Antibody
VANGL2 단백질을 인식하는 Thermo Fisher Scientific의 염소 폴리클로날 항체. Western blot에 적합하며, 마우스 반응성. 합성 펩타이드 면역원으로 제작, 0.5 mg/mL 농도의 액상 형태. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.3–1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (QKYLRTTKQQPYH) corresponding to internal amino acids of VANGL2 (aa 403–416) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_11009181 |
Product Specific Information
- Predicted to react with bovine and zebrafish based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 32,000.
Target Information
Van Gogh (strabismus protein in Drosophila) homolog VANGL2 is a 521 amino acid protein in vertebrates.
It is part of the frizzled–disheveled tissue polarity pathway and interacts through its C-terminal region with DVL1, DVL2, and DVL3.
Acts as a tumor suppressor and is involved in early morphogenesis, neural plate development, and regulation of planar cell polarity.
Essential for stereociliary bundle orientation in the cochlea and myocardial cell polarization via RHOA signaling.
Expressed in a wide range of tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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