Thermo Fisher Scientific MAPKAPK3 Polyclonal Antibody
MAPKAPK3 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunocytochemistry에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태이며, 인간 단백질에 반응. 연구용으로만 사용 가능.
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- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human MAPKAPK3. Recombinant protein control fragment (Product #RP-105099) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663392 |
Product Specific Information
- Immunogen sequence: RVDYDQVKIKD LKTSNNRLLN KRRKKQAGSS SASQGCNN
- Highest antigen sequence identity to the following orthologs: mouse 100%, rat 95%
Target Information
MAPKAPK3 functions as an integrative element of signaling in both mitogen and stress responses.
It acts as a mitogen-activated protein kinase (MAP kinase)-activated protein kinase.
MAP kinases, also known as extracellular signal-regulated kinases (ERKs), serve as integration points for multiple biochemical signals.
MAPKAPK3 is activated by growth inducers and stress stimuli. ERK, p38 MAP kinase, and Jun N-terminal kinase can phosphorylate and activate MAPKAPK3, highlighting its role in mitogen and stress response signaling.
MAPKAPK3 interacts with, phosphorylates, and represses the activity of E47, a transcription factor involved in tissue-specific gene expression and cell differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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