Thermo Fisher Scientific CDKN2B Monoclonal Antibody (OTI8H4), TrueMAB
인간 CDKN2B 단백질을 인식하는 마우스 모노클로날 항체로, Western blot, IHC, ICC/IF에 적합. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공. 연구용으로만 사용 가능하며 안정적 저장 조건 제공.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8H4 |
| Immunogen | Full length human recombinant protein of human CDKN2B produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The four known 15–19 kDa INK4 proteins (p15INK4b, p16INK4a, p18INK4c, and p19INK4d) bind and inhibit CDK4 and CDK6 but not other CDKs, including cyclin E-Cdk2, cyclin A-Cdk2, and cyclin B-Cdk1. Like the three D-type cyclins, the INK4 genes are expressed in distinct tissue-specific patterns, suggesting that they are not strictly redundant. p18INK4c is expressed during G1 to S transition in the eukaryotic cell division cycle and is maximally induced as cells enter S-phase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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