Thermo Fisher Scientific Seipin Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Seipin. Recombinant protein control fragment (Product #RP-90433). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Seipin,uniProtId:Q96G97-2,ncbiNodeId:9606,antigenRange:58-135,antigenLength:398,antigenImageFileName:PA5-59966_Seipin_Q96G97-2_Rabbit.svg,antigenImageFileNamePDP:PA5-59966_Seipin_Q96G97-2_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2647091

Product Specific Information

Immunogen sequence: PTVSHLSPVH FYYRTDCDSS TTSLCSFPVA NVSLTKGGRD RVLMYGQPYR VTLELELPES PVNQDLGMFL VTISCYTR

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 51%.

Target Information

This gene encodes protein seipin, which is located in the endoplasmic reticulum and may be important for lipid droplet morphology. Mutations in this gene have been associated with congenital generalized lipodystrophy type 2 or Berardinelli-Seip syndrome, a rare autosomal recessive disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.