Thermo Fisher Scientific CYP17A1 Monoclonal Antibody (OTI5G10), TrueMAB
CYP17A1 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot에 최적화됨. 인간 시료에 반응하며, HEK293T 세포에서 발현된 full-length CYP17A1 단백질을 면역원으로 사용. 액상 형태로 제공되며, -20°C에서 보관 권장. 연구용 전용 제품.
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Applications
- Western Blot (WB): 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5G10 |
| Immunogen | Full length human recombinant protein of human CYP17A1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. This protein localizes to the endoplasmic reticulum and has both 17α-hydroxylase and 17,20-lyase activities. It is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17α-hydroxylase deficiency, 17α-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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