Thermo Fisher Scientific XTP4 Polyclonal Antibody
Thermo Fisher Scientific의 XTP4 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며 Western blot, ELISA, IP에 사용 가능합니다. 친화 크로마토그래피로 정제된 고품질 항체로, 다양한 암 연구 및 단백질 발현 분석에 적합합니다.
- 카탈로그번호
- XTP4-141AP
- 판매단위
- pk
카탈로그
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Multiple epitope synthetic peptide taken within amino acid regions 1–50, 20–70, 40–90 and 80–130 on human XTP4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer (pH 7.4–7.8) with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20 °C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
During the past decade, the role of the ERBB2 (neu/HER2) oncogene as an important predictor of patient outcome and response to various therapies in breast cancer has been clearly established. The C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer. Identification of shared tumor-specific targets is useful in developing broadly applicable therapies. The C35 gene is located on chromosome 17q12, 505 nucleotides from the 3′ end of the ERBB2 oncogene, the antigenic target for trastuzumab (Herceptin) therapy. The chromosomal arrangement of the genes encoding C35 and ERBB2 is tail to tail. The ORF 37 open reading frame encodes a 12 kDa protein of unknown function.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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