Thermo Fisher Scientific Phospho-EPB41 (Tyr418, Tyr660) Polyclonal Antibody
Phospho-EPB41 (Tyr418, Tyr660) 항체로 인간 및 생쥐 시료에서 인산화된 EPB41 단백질 검출에 적합. Western blot에 최적화되어 있으며, HepG2 세포를 양성 대조군으로 권장. 친화 크로마토그래피로 정제된 고순도 Rabbit IgG 폴리클로날 항체.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
Suggested positive control: HepG2 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 660/418 (N-I-Y(p)-I-R) derived from Human EPB41 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2554169 |
Product Specific Information
A suggested positive control for Western blot is HepG2 cells.
Target Information
Elliptocytosis is a hematologic disorder characterized by elliptically shaped erythrocytes and a variable degree of hemolytic anemia. It is inherited as an autosomal dominant trait and results from mutations in genes encoding red cell membrane skeleton proteins. The form linked to the Rh blood group is caused by a defect in protein 4.1, while Rh-unlinked forms of elliptocytosis are caused by mutations in the alpha-spectrin, beta-spectrin, or band 3 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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