Thermo Fisher Scientific BNIP3 Monoclonal Antibody (ANa40)
BNIP3 단백질을 인식하는 Mouse monoclonal antibody (Clone ANa40). Western blot, IHC, ICC, ELISA, IP에 사용 가능. Human 시료 반응성. Protein A 정제, 2.4 mg/mL 농도. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 2–4 µg/mL | - |
| Immunohistochemistry (IHC) | Assay-dependent | 1 publication |
| Immunocytochemistry (ICC/IF) | Assay-dependent | - |
| ELISA | Assay-dependent | - |
| Immunoprecipitation (IP) | Assay-dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | ANa40 |
| Immunogen | Recombinant fragment corresponding to residues 1–163 of human BNIP3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.4 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term, store at -20°C avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2066655 |
Product Specific Information
- Positive Control: 293T cells transfected with BNIP3.
Target Information
NIP3 is a member of the BCL2/adenovirus E1B 19 kDa-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects against virally induced cell death, as well as BCL2, another apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain associated with pro-apoptotic function. This dimeric mitochondrial protein can induce apoptosis even in the presence of BCL2.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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