Thermo Fisher Scientific OX40L Polyclonal Antibody
OX40L 단백질을 표적하는 Rabbit Polyclonal Antibody로 인간, 마우스, 랫트 반응성이 있음. Western blot 및 IHC에 사용 가능. 항원 친화 크로마토그래피로 정제된 액상 형태이며, PBS 버퍼와 0.02% sodium azide 포함. 연구용으로 적합.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.5–1 µg/mL |
| Immunohistochemistry (IHC) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 14 amino acid peptide near the carboxy terminus of human TNFSF4 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551868 |
Product Specific Information
- A suggested positive control is rat spleen tissue lysate.
- PA5-34516 can be used with blocking peptide PEP-1559.
Target Information
The tumor necrosis factor superfamily member TNFSF4 is a type II membrane-bound, non-covalently linked homotrimeric protein.
It is expressed on antigen-presenting cells such as dendritic cells and activated B-cells, as well as vascular endothelial cells, mast cells, and natural killer cells.
TNFSF4 signals specifically through the TNFRSF4 receptor, expressed predominantly on CD4+ T cells and certain activated CD8+ T cells.
This signaling functions as a costimulatory mechanism required for productive interaction between antigen-presenting cells and target T-cells.
It enhances cell proliferation, survival, and increases expression of RANTES, IL-2, IL-3, and IFN-γ.
TNFRSF4/TNFSF4 signaling plays an important role in immunotolerance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-34516_OX40L_CD252_P23510-1_Rabbit.svg, PA5-34516_OX40L_CD252_P23510-1_Rabbit_PDP.jpeg)
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