Thermo Fisher Scientific IFN alpha Monoclonal Antibody (F18)
Thermo Fisher Scientific의 IFN alpha Monoclonal Antibody (F18)는 마우스 IFN-α를 인식하고 중화하는 랫 IgG1 단클론 항체입니다. Western blot, Flow cytometry, Functional 및 Inhibition assay에 적합하며, PBS/BSA 버퍼에 보존된 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- MA549050
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:50 |
| Flow Cytometry (Flow) | 1:50 |
| Functional Assay | 1:50 |
| Inhibition Assay (IA) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | F18 |
| Immunogen | The monoclonal antibody F18 recognizes and neutralizes both natural and recombinant mouse alpha Interferon (IFN-alpha). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 100 µg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 0.1% BSA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_3093498 |
Product Specific Information
The monoclonal antibody F18 recognizes and neutralizes both natural and recombinant mouse alpha Interferon (IFN-alpha).
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins found in vertebrates. Interaction of IFN-alpha with its receptor activates multiple signaling pathways involved in the innate immune response against viral infection. In humans, the gene for IFN alpha is located on chromosome 9. Type I interferons include 14 alpha isoforms, and single beta, omega, epsilon, and kappa isoforms. Homologous molecules exist in many species including rats, mice, birds, reptiles, and fish. IFN alpha is produced primarily by plasmacytoid dendritic cells and acts as a potent component of the antiviral innate immune response while modulating adaptive immunity. Dysfunctions in IFN alpha are associated with diseases such as Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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