Thermo Fisher Scientific AXUD1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human AXUD1. Recombinant protein control fragment (Product #RP-106858). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:AXUD1,uniProtId:Q96S65-1,ncbiNodeId:9606,antigenRange:128-197,antigenLength:589,antigenImageFileName:PA5-66174_AXUD1_Q96S65-1_Rabbit.svg,antigenImageFileNamePDP:PA5-66174_AXUD1_Q96S65-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2664487

Product Specific Information

Immunogen sequence: FAQEQARARHE KLRQRLKEEK LEMLQWKLSA AGVPQAEAGL PPVVDAIDDA SVEEDLAVAV AGGRLEEVS

Highest antigen sequence identity to the following orthologs - mouse 76%, rat 79%.

Target Information

Axin, an important regulator of beta-catenin, is frequently mutated in human hepatocellular carcinomas (HCCs), and transduction of the wild-type Axin gene (AXIN1) induces apoptosis in HCC cells as well as in colon cancer cells. A novel gene, AXUD1 (AXIN1 up-regulated), has enhanced expression in response to exogenously expressed AXIN1. It is expressed in all human tissues examined, most abundantly in lung, placenta, skeletal muscle, pancreas and leukocytes. Data suggests that AXUD1 may have a tumor-suppressor function in those organs.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.