Thermo Fisher Scientific C9orf7 Polyclonal Antibody
C9orf7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. 고순도 Protein A 정제, 1 mg/mL 농도, 안정적인 액상 형태로 제공.
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Thermo Fisher Scientific C9orf7 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human C9orf7 (amino acids 41–130) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Transmembrane protein mediating synaptic endocytosis and fitness-based cell culling. Controls two major modes of synaptic vesicle retrieval in hippocampal neurons: clathrin-mediated endocytosis (CME) under mild stimulation and activity-dependent bulk endocytosis (ADBE) under strong stimulation. In cytotoxic T-lymphocytes, facilitates calcium-dependent endocytosis of cytotoxic granules at the immuno synapse. Different isoforms act as fitness fingerprints in "loser" and "winner" cells, mediating cell competition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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