Thermo Fisher Scientific CaMKII beta Monoclonal Antibody (CB-beta-1)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

View 25 publications 25 publications

Immunohistochemistry (IHC)

Assay-dependent

View 2 publications 2 publications

Immunocytochemistry (ICC/IF)

-

View 5 publications 5 publications

ELISA (ELISA)

Assay-dependent

-

Immunoprecipitation (IP)

Assay-dependent

View 2 publications 2 publications

Miscellaneous PubMed (Misc)

-

View 1 publication 1 publication

Product Specifications

Species Reactivity

Fish, Human, Mouse, Sheep, Rat, Sea urchin

Published species

Human, Mouse, Non-human primate, Rat

Host/Isotype

Mouse / IgG2b, kappa

Class

Monoclonal

Type

Antibody

Clone

CB-beta-1

Immunogen

Purified rat brain CaM Kinase. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CaMKII beta,uniProtId:P08413-1,ncbiNodeId:10114,antigenRange:1-542,antigenLength:542,antigenImageFileName:13-9800_CaMKII_beta_P08413-1_House_mouse.svg,antigenImageFileNamePDP:13-9800_CaMKII_beta_P08413-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.5 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

-20°C

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2533045

Target Information

CAMK2B (CaMKII beta) is a serine/threonine kinase that plays a role in synaptic plasticity, synaptic vesicle mobilization and regulation of gene expression. As a dominant kinase in the central nervous system it may function in long term potentiation and neurotransmitter release. There are four CaMKII isozymes, designated alpha, beta, gamma and delta, which may or may not be co-expressed in the same tissue type. CaMKII alpha is autophosphorylated on Thr 286 upon the binding of the Ca2+/CaM complex to the autoinhibitory domain of CaMKII. This process is called Ca2+/CaM trapping, which is thought to be involved in the synaptic encoding of information.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.