Thermo Fisher Scientific Bit1 Polyclonal Antibody
Bit1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 인간 시료 반응성이 있습니다. 액상 형태로 제공되며 -20°C에 보관합니다.
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Thermo Fisher Scientific Bit1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution
- 1:1,000
Publications
- [참고 문헌 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues within a central region of Bit1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 100µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10981292 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
The protein encoded by this gene is a mitochondrial protein with two putative domains: an N-terminal mitochondrial localization sequence and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, releasing the peptidyl moiety from tRNA to prevent accumulation of dissociated peptidyl-tRNA that could reduce translation efficiency.
This protein also plays a role in regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix. Mutations are associated with intellectual disability, postnatal microcephaly, progressive cerebellar atrophy, hearing impairment, polyneuropathy, failure to thrive, and organ fibrosis with exocrine pancreas insufficiency.
Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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