Thermo Fisher Scientific PSG1 Polyclonal Antibody
Human PSG1 단백질을 인식하는 Rabbit Polyclonal 항체로, WB 및 IHC(P) 실험에 적합합니다. N-말단 합성 펩타이드로 면역화되었으며, Protein A로 정제된 액상 포맷입니다. PBS(2% sucrose) 버퍼에 보관하며, 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 4–8 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human PSG1 (aa 96–145) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2609493 |
Product Specific Information
- Peptide sequence: SGRETAYSNA SLLIQNVTRE DAGSYTLHII KGDDGTRGVT GRFTFTLHLE
- Sequence homology: Human: 100%
Target Information
Human pregnancy-specific glycoproteins (PSG) are a group of closely related secreted glycoproteins highly expressed in placental syncytiotrophoblast cells of fetal origin. PSGs are commonly expressed in tumors of trophoblast origin (e.g., hydatidiform mole, choriocarcinoma) and represent the most abundant fetal protein in maternal blood at term.
The eleven human PSG genes (PSG1–PSG11) form, together with the carcinoembryonic antigen (CEA)-related cell adhesion molecule (CEACAM) genes, the CEACAM gene family. PSG stimulates secretion of TH2-type cytokines from monocytes, and CD9 has been identified as the monocyte receptor for murine PSG17. PSGs are thought to modulate the maternal immune system during pregnancy, protecting the semiallotypic fetus from rejection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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