Thermo Fisher Scientific NR3C2 Polyclonal Antibody

Thermo Fisher Scientific NR3C2 Polyclonal Antibody

Applications and Tested Dilution

Product Specifications

Product Specific Information

• Positive Samples: HeLa, 293T, Mouse liver, Mouse kidney, Rat liver
• Immunogen Sequence:
  FPFMDGSYFS FMDDKDYYSL SGILGPPVPG FDGNCEGSGF PVGIKQEPDD GSYYPEASIP SSAIVGVNSG GQSFHYRIGA QGTISLSRSA RDQSFQHLSS FPPVNTLVES WKSHGDLSSR RSDGYPVLEY IPENVSSSTL RSVSTGSSRP S

Target Information

Steroid receptors are ligand-dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone.
Mineralocorticoids are a family of steroids secreted by the adrenal cortex, necessary for the regulation of metabolic processes including electrolyte balance.
They exert their effect through interaction with the mineralocorticoid receptor (MR) and subsequent association with DNA.
The kidney is a primary target organ for mineralocorticoids, containing abundant MR.
The corresponding gene for the mineralocorticoid receptor is NR3C2.

Safety Information

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.