Thermo Fisher Scientific NOS1AP Polyclonal Antibody
NOS1AP 단백질을 인식하는 Thermo Fisher Scientific의 rabbit polyclonal antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간 시료 반응성, 고순도 항원 친화 크로마토그래피 정제. 장기 보관 시 -20°C 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NOS1AP. Recombinant protein control fragment (Product #RP-102562). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644750 |
Product Specific Information
Immunogen sequence:
HTGSKVSHPQ EPMLTASPRM LLPSSSSKPP GLGTETPLST HHQMQLLQQL LQQQQQQTQV AVAQVHLLKD QLAAEAAARL EAQARVHQLL LQNKDMLQHI SLLVK
Highest antigen sequence identity to the following orthologs:
- Mouse: 95%
- Rat: 93%
Target Information
This gene encodes a cytosolic protein that binds to the signaling molecule neuronal nitric oxide synthase (nNOS). It contains a C-terminal PDZ-binding domain mediating interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein Dexras1. Studies show that this protein functions as an adapter linking nNOS to specific targets such as Dexras1 and synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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