Thermo Fisher Scientific XPA Polyclonal Antibody
XPA 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 마우스, 랫트 반응성. 고순도 Affinity Chromatography 정제, 액상 형태로 -20°C 보관.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human XPA (Accession P23025), corresponding to amino acid residues H171–K221 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851852 |
Product Specific Information
Antibody detects endogenous levels of total XPA.
Target Information
The XPA (xeroderma pigmentosum group A) protein specifically recognizes UV or chemically damaged DNA lesions and triggers the nucleotide excision repair process.
XPA binds to replication protein A (RPA) or excision repair cross complementing 1 protein (ERCC1).
In the absence of nucleotide excision repair, unrepaired DNA lesions may lead to gene mutations and ultimately to cancer.
Xeroderma pigmentosum patients have a >2000-fold increased risk of developing skin cancer in sun-exposed areas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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