Thermo Fisher Scientific KHDC1 Monoclonal Antibody (OTI2G6), TrueMAB
KHDC1 단백질을 인식하는 Mouse IgG2a 단클론 항체로 Western blot에 적합. 인간 시료 반응성, 고순도 친화 크로마토그래피 정제. 액상 형태로 안정적이며 -20°C 보관. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2G6 |
| Immunogen | Full length human recombinant protein of human KHDC1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
KHDC1 family members are K-homology (KH) domain-containing RNA binding proteins involved in various aspects of RNA metabolism, including transcription, splicing, transportation, translation, and stability. KHDC1 is highly expressed in oocytes and interacts with cytoplasmic polyadenylation element-binding protein 1 (CPEB1), a key translational regulator controlling the polyA length of mRNAs. KHDC1 functions as a global translational repressor and induces apoptosis through an ER-dependent signaling pathway. The C-terminal putative trans-membrane motif (TMM) is critical for its activities.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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