Thermo Fisher Scientific TGFBR3 Monoclonal Antibody (OTI6B2), TrueMAB
인간 TGFBR3 단백질(aa 531-777)에 특이적인 Mouse IgG1 단클론 항체. Western blot에 적합하며, 동결건조 형태로 제공. PBS(pH 7.3, 8% trehalose) 버퍼에 보존, 보존제 없음. -20°C에서 보관, 재동결/해동 피할 것.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6B2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 531–777 of human TGFBR3 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
The TGFBR3 gene encodes the transforming growth factor (TGF)-beta type III receptor, a membrane proteoglycan that functions as a co-receptor with other TGF-beta receptor superfamily members.
Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers.
Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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