Thermo Fisher Scientific MDFIC Polyclonal Antibody
Rabbit polyclonal antibody targeting human MDFIC protein. Suitable for IHC (Paraffin) applications with 1:25–1:100 dilution. Detects endogenous MDFIC isoforms involved in transcriptional regulation. Provided in liquid form, purified by antigen affinity...
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:25–1:100 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human MyoD family inhibitor domain containing |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2636158 |
Product Specific Information
The antibody detects endogenous levels of total MDFIC protein.
Target Information
MDFIC is a member of a family of proteins characterized by a specific cysteine-rich C-terminal domain, which is involved in transcriptional regulation of viral genome expression.
Alternative translation initiation from an upstream non-AUG (GUG) and an in-frame downstream AUG codon results in the production of two isoforms, p40 and p32, respectively, which have different subcellular localizations: p32 is mainly found in the cytoplasm, whereas p40 is targeted to the nucleolus.
Both isoforms have transcriptional regulatory activity attributable to the cysteine-rich C-terminal domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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