Thermo Fisher Scientific KV1.6 (KCNA6) Polyclonal Antibody
Thermo Fisher Scientific의 KV1.6 (KCNA6) 폴리클로날 항체는 인간 유래 단백질에 반응하는 Rabbit IgG 항체로, ICC/IF에 0.25–2 µg/mL 농도로 사용 가능합니다. 고순도 친화 크로마토그래피 정제 제품이며, 장기 보관 시 -20°C에서 안정적으로 유지됩니다. 연구용 전용 시약입니다.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence (range: 473–522). Recombinant protein control fragment: Product #RP-110023 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.4 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C (avoid freeze/thaw cycles) |
| Shipping Conditions | Wet ice |
| RRID | AB_3091985 |
Product Specific Information
- Immunogen sequence:
EQGQYTHVTC GQPAPDLRAT DNGLGKPDFP EANRERRPSY LPTPHRAYAE - Antigen sequence identity:
- Mouse: 92%
- Rat: 90%
Target Information
Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include:
- Regulating neurotransmitter release
- Heart rate control
- Insulin secretion
- Neuronal excitability
- Epithelial electrolyte transport
- Smooth muscle contraction
- Cell volume regulation
Four sequence-related potassium channel genes — shaker, shaw, shab, and shal — have been identified in Drosophila, each with a human homolog.
This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. It contains six membrane-spanning domains with a shaker-type repeat in the fourth segment and belongs to the delayed rectifier class. The coding region is intronless, and the gene is clustered with KCNA1 and KCNA5 on chromosome 12.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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